Archive for Peptide explanations

The 411 of Research Peptides

Many people do not fully understand what a peptide is and haven’t worried about them since chemistry class in high school. To medical researchers, pure peptides are very important to research and can assist experiments where they replicate processes within the human body. Peptides are present in every living cell in form of enzymes, receptors, antibiotics and hormones to act as an integral part activity within the body.

Those unfamiliar with Peptides, they are links of amino acids that is dictated by gene sequences. Proteins will on average be 270 amino acids in length, but relatively short chains, fewer than 50 proteins, are known as peptides. Peptides help our bodies build our structure, catalyze reactions, regulate and protect and transport substances throughout the body.

How are these peptides made you might ask? Amino acids are the building blocks of peptides and proteins. Amino acids have an amino (-NH2) connected to a carboxylic acid (-COOH). Connected they form an amino acid. From that point there are variations that help in the creation of the plethora of uses that peptides help complete.

These pure peptides can reproduce situations that occur within our bodies to produce basic biological research, peptide – based drugs and peptide – based materials. Some of these experiments include protein structure/function, HIV treatments and an even more advanced usage includes using peptides in materials such as scaffolds for tissue engineering.

Peptides are found in vast amount of processes throughout the body. For example the hemoglobin in your blood is formed by peptides and helps carry oxygen in your blood to vital organs, help build bones and cartilage and regulate chemical reactions within cells. Outside the body pure peptides, like those offered by Crown Peptides are pure peptides like those found naturally in your body helping with the research of Antibiotics, HIV treatment and cancer prevention.

peptide offer synthetic research peptides that are useful in replicating the structure and functionality of the same processes that occur within the human body. This has enabled scientific researchers to be able to examine proposed reactions of their new treatments to ensure the correctness of their hypothesis. Superior Peptides guarantees a 98.6% purity across their selection of GHRP-6, Melanotan II, Ipamorelin and research peptides. For those looking for a secure online source to purchase research peptides Crown Peptides has 7 years in the research industry and has an unparalleled customer service.

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Peptide mixing Information

Peptide mixing Information

Peptides come in the form of lyophilized (freeze dried) powder. The amount of powder/product is stated in International Units (IU’s) or in Milligrams (MG).
Melanotan peptides (Melanotan 1 & Melanotan 2), PT-141 Bremelanotide, GH Fragment, Ipamorelin, CJC-1295 & GHRPs (GRHP-2 & GHRP-6), HGH, HCG, et cetera use Bacteriostatic Water (BW). Bacteriostatic Water for injection, USP is a sterile, nonpyrogenic preparation of water for injection containing 0.9% of benzyl alcohol added as a bacteriostatic preservative. It is supplied in a multiple-dose container from which repeated withdrawals may be made to dilute or dissolve drugs for injection. The pH is 5.7 (4.5 to 7.0)

For IGF use an acetic acid solution (.6%) which is 7 parts distilled water and 1 part vinegar to reconstitute. You must filter the distilled water and white wine vinegar through a sterile 20 micron syringe filter before use. Sodium Chloride (NaCl) is used to buffer the injection.

1.) Take an alcohol swab to the stopper of both your peptide vial and the vial of the diluent.

2.) Draw your preferred diluent (BW) with a 1cc syringe. Choose an amount that will make measuring the final product simple.

1ml(cc) per 10 mg vial of Melanotan would mean each 10 tick marks on a U100 slin syringe would equal 1mg of Melanotan
1ml(cc) per 10 IU vial of HGH would mean each 10 tick marks on a U100 slin syringe would equal 1 IU of HGH

3.) Take the syringe with the diluent and push it into the vial of lyophilized powder letting the diluent dissolve the peptide. Many (not all) peptides are sealed with vacuum pressure, be careful.

4.) After diluent has been added to the vial, gentling swirl the vial until the lyophilized powder has dissolved and you are left with a clear liquid. The peptide is now reconstructed, ready for measurement and usage.
5.) Store your now reconstituted research peptides in the refrigerator.
Peptide Measurement
After successfully reconstituting your peptide, measure the desired amount out for injection. Use a U100 insulin syringe to draw out and inject your product.

Since you know the amount of IU’s/MG’s in your vial, we divide this out as follows:
You will need to know the following to be successful: 1ml = 1cc = 100 IU’s

We take our dose from the label of the dry lyophilized powder and we divide that into the amount of diluent used.

Example- We used 1cc(ml) of water. We have a 10 IU vial of HGH.
From our formula above we know that 1cc = 100 IU’s, so we have 100 IU’s of water.
We now divide the 100 IU’s (the amount of our water) by 10 IU’s (the amount of our HGH)
100 IU / 10 IU = 10

This 10 will perfectly correspond with the markings on a U100 insulin syringe. In our example every 10 mark on our syringe will equal 1 IU of HGH. Want to draw out 2 IU’s of GH? ….draw out to the 20 mark on the syringe (1/5th of the syringe).

Say you have a 1mg vial and you add 1ML you get
1000mcg/1mL: 10 mcg per IU
1000mcg/2mL: 5 mcg per IU

Say you have a 10mg vial and you add 1ML you get
10mg/1mL: 1 mg per 10 IU
10mg/2mL: .5 mg per 10 IU

Say you have a 20mg vial and you add 1ML you get
20mg/1mL: 2 mg per 10 IU
20mg/2mL: 1 mg per 10 IU

Say you have a 10iu vial and you add 1ML you get
10iu/1mL: 1 iu per 10 IU (on the syringe – 1/10th the product)
10iu/2mL: 1 iu per 20 IU (on the syringe – still 1/10th the product)

Say you have a 5000iu vial and you add 1ML you get
5000iu/1mL: 500iu per 10 IU
5000iu/2mL: 250iu per 10 IU

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