Melanotan II the breakdown

Melanotan II the breakdown

Melanotan is a peptide that is produced in the body as a way of making an animal’s skin tan. This is used as a response to exposure to UV rays to protect the animal’s body against skin cancer and other damage. This chemical has been synthesized as Melanotan 2, which was developed by researchers at the University of Arizona. This synthetic analog mimics the behaviors of the melanocortin peptide hormone alpha-melaocyte stimulating hormone.

The synthetic version of this peptide has been found to produce similar melanogenesis effects and aphrodisiac effects in animal test subjects, in the initial clinical trials that have been performed. To date, no compounds that contain melanotan 2 peptides have been approved for human use as clinical trials are still ongoing. However, initial research indicates that this peptide may be very useful in preventing a variety of cancers and other diseases if the effects of it can be regulated to minimize side effects.

This has increased the desire for bulk purchases of this peptide. There are a variety of ways to secure melanotan 2 for research purposes, but a great deal of care will need to be given in order to ensure that the product you purchase is the proper quality for this purpose.

Warnings for Melanotan Shoppers

 

Because products containing melanotan have not been approved for the public market, the variety of products that claim to contain these ingredients actually don’t.

Products that contain any form of melanotan 2 are not allowed to be sold for human use; there are a variety of items online that claim to contain this ingredient because they have been manufactured in markets that do not have a ban on melanotan.
In many cases these products contain fraudulent ingredients that are designed to mimic the effects of melanotan 2 to take advantage of less than credible customers. There are a variety of regulatory bodies that are currently attempting to catalogue these products and issue a warning to those that might attempt to purchase them due to the severe risk of interacting with these unknown chemical mixes.
Those that are investing in melanotan as part of a research study can save a great deal of money and time by purchasing stores of melanotan from internet retailers, but the same risks that are posed to customers attempting to bend the rules may apply to these research facilities as well. If a product claims to contain melanotan 2, but is actually a counterfeit product, it could throw off research results. This could also pose a danger for animal test subjects which could experience unpredictable side effects that could be life threatening.
In order to eliminate the risk of working with counterfeit products during research, scientists should only purchase melanotan 2 from companies that are certified to sell research quality peptides.

These products will be sterilized and contain a specific list of the methods used to create the peptide so that researchers can ensure that they can predict how these chemicals will behave in chemical trials when they are applied to animal test subjects. This will also ensure that any bulk purchases are consistent to avoid any potential for an alteration of reactions during clinical trials that cannot be accounted for.

Evolution of Melanotan Development

Pilot studies using cylic heptapeptide analogs of aMSH and melanotan 2 have found to have super potent melanotropic activities in vitro.

Aingle blind studies utilizing alternating day trials with placebo controlled trials were conducted on male animal test subjects with initial applications of .01mg/kg of melanotan 2. Subcutaneous injections of saline or melantotan 2 were applied daily during weekdays for two weeks.
Two of the test subjects saw an increase in the increments of melanotan applications with .0005, .03 and .025mg/kg applications given throughout the length of the study. In these two subjects, .03mg/kg applications and higher were found to cause fatigue and somnolence.
Test subjects given applications of melanotan also showed signs of mild nausea at most dosing levels. Stretching and yawning complex appeared to correlate with applications around 1-5 hours after the chemical was applied. However, the length of time between these reactions appeared to correlate with the size of the application of melanotan 2 that was provided.
Of the three test subjects that were used in this study, two saw increased pigmentation around the face and upper body which was determined by comparing pictures of the test subjects against visual perception a week into the study. This was also compared a week after applications of melanotan 2 had ceased. These results help to demonstrate the tanning ability of melanotan 2 at 5 low applications up to 5 days of subcutaneous injections can provide.

It is currently recommended for future animal research that applications begin at single applications of .025mg/kg a day in animal test subjects, though this can be increased– based on the animal’s reaction to the chemical and the size of the test subject.

Additional Considerations for Melanotan Research

Much of the research surrounding melanotan focuses on mimicking the peptides that are naturally found in animal skin, but there are some uses for this product that could pose for additional promise for the future use of melanotan 2 products.

Melanotan was initially designed to mimic the chemicals in an animal’s body that are used to darken the skin tone as a protective barrier against UV rays from the sun. This pigment can also be released after the skin is damaged, which can lead to the pigmentation which is shown in an area that has been scarred, though this is an effect that need not be replicated in a pharmaceutical setting.
If this reaction can be mimicked with an artificial version of melanotan 2 it could be used as a means of tanning the skin to prevent damage, including skin cancer, which is caused by overexposure to the sun. Some would also like to use melanotan 2 for cosmetic reasons, causing the skin to take on an attractive tan color without the unnecessary risks that are associated with staying out in the sun or using tanning beds.
At this time melanotan has not been developed to the point where it can create a controlled reaction by an animal’s body, which is restricting researcher’s ability to release products containing this peptide to the public.
Because melanocortin naturally has a very short half-life, the peptide has been altered to create melanotan 2. This altered chemical composition has been found to be helpful in creating a peptide that has a longer shelf life and effectiveness when exposed to the bloodstream. These altered chemical bonds within the peptide have been found to have alternative effects, when exposed to animal tissues. This altered reaction may be helpful in allowing this peptide to be used for previously unpredicted chemical reactions.

Melanotan has been found to cause a variety of side effects in test subjects during clinical trials. Even low applications in animals could cause nausea, stretching and yawning. Male animals have also been found to experience spontaneous penile erections when they are exposed to melanotan 2 applications.

These side effects on their own are not typically considered to be dangerous for test subjects involved in this research, but it is believed that larger applications could impact the severity of these side effects, which should be accounted for when working with a variety of animals during study.

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