Most if not everything you need to know in relation to research peptides..
Melanotan One, Scenesse, Afamelanotide (M-I)
Melanotan/Afamelanotide is a synthetic version of melanocyte
stimulating hormone (a-MSH). Afamelanotide has been shown to induce skin
pigmentation through melanogenisis, the production of melanin. Melanin prevents
cellular damage in the skin by absorbing, reflecting and refracting light.
Melanotan reduces sun damage to UV exposed skin in those with sun allergies.
favors production of eumelanin (black/brown) over pheomelanin (red/yellow)
pigment. Injecting this linear amino acid structure peptide offers
super-physiological levels of a-MSH. Learning the majority of secretion of a-MSH
comes from the skin as opposed to the pituitary gland was a recent breakthrough
in medical science. Those with a Fitzpatrick skin type I-III classification have
natural levels of a-MSH that are hardly detectable. The fair skinned can achieve
a photoprotective tan with synthetic MSH.
half-life of Melanotan peptides is very brief. Afamelanotide is being developed
in implant form for the ease of use in dermatology. The implant contains 16mg
which has a controlled release effecting melanin density for months. Melanotan
One is offered in research peptide form (20mg Melanotan One). Peptide Melanotan
One gives the user greater control over dosing, however requires a series of
injections and expertise. Missing a dose or taking time off is okay.
Intermittent therapy, lasting 10 days (skin type III) to 6 months (skin type I)
is typical for researchers.
amino acids present in the bodies natural a-MSH have been changed in production
of Afamelanotide creating a more stable molecule.
Amino acid sequence:
still undergoing clinical trials and has not reached approved status. People use
on the pretenses and understanding that it is for research purposes only. Users
may suffer from slight nausea and flushing after subcutaneous injection; however
it is reported to be mild and pass quickly.
Melanotan One is a selective
agonist of the MC1R (Melanocortin 1 receptor) and does not have aphrodisiac
effects. Melanotan One does not cross the blood brain barrier (BBB). It is for
this reason Afamelanotide has continued clinical trials. The fat/weight loss,
appetite suppression, libido effects are found in Melanotan 2 and Bremelanotide
Melanotan One is less efficacious than its counterpart
Melanotan 2 for achieving a dark tan. Afamelanotide will therefore require 8-10x
the dosage to see comparable results. Melanotan One users want minimum side and
peripheral effects with a focus on photoprotection.
Safe and controlled administration of Afamelanotide for
research is done much like that of Melanotan 2. Melanotan One offered as a
peptide in a multi-dose sterile vial is desirable. Implants, nasal sprays and
pills are not applicable/efficacious at the present time.
Allow time before seeing UV exposure. Sunburn is to be avoided.
Example- Skin type II, 180lb male
Day 1-2: .5mg each night
3-6: 1mg when convenient
Day 7-10: 2mg when convenient
Day 11 on forward:
begin dosing ~6mg/week
Day 7: 10min sun bed session. (Cover
face/genitals/sun damage, use lotion, etc)
Day 9: 10min sun bed session.
Day 11: 15min sun bed session
Dosing According to Skin
Fitzpatrick Skin Type I: 1mg-2mg/day. 100mg total may be necessary
to achieve desired color. UV exposure after at least 20mg in
Fitzpatrick Skin Type II: .75mg-1.5mg/day. 60mg should be sufficient
to get color. UV exposure after 10-20mg
Fitzpatrick Skin Type III:
.5mg-1mg/day. A sunless tan may be realistic here
Fitzpatrick Skin Type IV
and beyond: Do not use Melanotan
Melanotan can develop a protective tan
in users. A natural tan is developed in response to cell damage caused by UV
radiation. Ultraviolet rays penetrate the upper layers of the skin, triggering
a-MSH, stimulating melanin production. Melanin deposits act as a natural
sunblock at the cellular level. Melanotan injections may offer a way to bring
upon a safe, cosmetic tan with less damage.
the stopper of both your M-I vial and the vial of the dilutent (bacteriostatic
water) with an alcohol swab.
Take a syringe and draw up your bact water.
The amount isn’t critical, other than making sure you know exactly how much you
have used. The best rule of thumb is choose an amount that will make measuring
the final product easy.
Example- 2ml(cc) per 20mg vial of M-I would mean
each 10 marks on a U100 insulin syringe would equal 1mg of Melanotan
Example- 1ml(cc) per 10mg vial of M-I would mean each 10 marks on a
U100 insulin syringe would equal 1mg of Melanotan (M-I)
the dilutent directly on the lyophilized powder. The powder should almost
instantly dissolve. Gently swirl until the liquid is clear if powder did not
dissolve upon contact.
Store your unused M-I in the refrigerator. Once
reconstituted, the Melanotan should be good for 4-6 weeks in the refrigerator.
After successfully reconstituting your peptide, now
measure the desired amount out for injection. You will want to use a U100
insulin syringe to draw out your M-I.
Since you know the amount of mg’s
in your M-I vial, and you also know how much water you have diluted it with, we
just divide this out as follows:
Note: 1ml = 1cc = 100 IU’s
So we take
our number of mg’s of Melanotan and we divide that into the amount of dilutent
Example- We used 2cc(ml) of water. We have a 20mg vial of
From our formula above we know that 1cc = 100 IU’s, so we have 200 IU’s
We now divide the 200 IU’s (the amount of our water) by 20mg (the
amount of our M-I)
200 IU / 20mg = 10
This 10 will perfectly
correspond with the markings on a U100 insulin syringe. In our example every 10
increments (1/10th of the syringe) on our syringe will equal 1mg of M-I.
Melanotan 2 Dosing:
Melanotan 2 (MT-II) is an analog of alpha-melanocyte
stimulating hormone (a-MSH). Melanotan 2 comes in the form of a freeze dried
(lyophilized) peptide in a sterile multi-use vial.
2 acts on melanocytes to stimulate melanin production. Melanin is the body’s
natural pigment responsible for your tan.
are a family of peptides beginning with the sequence: His-Phe-Arg-Trp. Melanotan
peptides bind to and activate melanocortin receptors (MCRs) which influence
pigmentation, inflammation, energy homeostasis, appetite and sexual function.
MT-2 MCRs: MC1R, MC3R, MC4R & MC5R.
Melanotan 2 is a smaller and more
potent than M-I (which targets MC1R) targeting more receptors. Melanotan 2 has a
protective ring-like amino acid structure as compared to a linear peptide such
as Melanotan One or Afamelanotide.
does this mean? The fair skinned CAN achieve a natural tan with synthetic MSH,
Melanotan 2. For people with sun allergies these discoveries are life changing.
The best defense against skin cancer is a natural tan developed over time. MT-2
was designed to reduce skin cancer rates and be effective as a sunless
Who uses Melanotan 2? Athletes and fitness enthusiasts choose
MT-2 as a lifestyle product to increase tanning efficacy, the aphrodisiac and
appetite suppression. MT-2 was dubbed the Barbie drug and has been highlighted
in wired. Synthetic melanocortin use helps to attain a tan with the least amount
of exposure to harmful ultraviolet radiation (UVR).
skin types on the Fitzpatrick scale are the best candidates for Melanotan
treatment stimulates melanin effectively, in particular those with low skin
Melanotan is approximately 1,000 times more potent than natural a-MSH and MT-2
has a greater efficacy than M-I.
Disclaimer: Please pursue information
regarding the usage of these products from your own research, academic journals,
or the research of your in-house scientific team. Products are sold for research
purposes are not for human consumption. Remember when you contact these types of
stores/sponsors not to relate the questions or topics to human
consumption or they tend not to answer. Always inquire in a research type
Melanotan 2 Peptide: Melanotan 2 peptides come in 5mg and 10mg
sizes. Photograph at left shows a 5mg and 10mg MT-2 peptide as an example.
Peptides within photograph were synthesized by the same laboratory, contain no
filler and therefore volume reflects content. All peptides and freeze drying
processes are not created equal. Current MT-2 industry standard is the 10mg, 2ml
vial size. Trending towards lower doses, freshness, safety, travel and other
factors are increasing demand for smaller quantities.
bacteriostatic water (BW), MT-2 peptide remains potent and preserved.
Reconstituting (mixing) your Melanotan 2 peptide is a necessity and will require
proper due diligence for results. Nasal sprays, pre-mixed Melanotan 2, pills,
oral and loose powder are not often legitimate. There are successful reports of
nasal spray experiences, however, they are few and far between as the molecule
is larger than the membrane will allow. Enzymes will render the peptide inactive
Shipping and Handling: Melanotan peptides are durable and
stable. Highlighted in study, the reconstituted MT-2 was shown to be stable at
37 degrees Celsius (98 degrees Fahrenheit) for at least 28 days. Shipping MT-2,
even in summer months, is not a problem. Do not pay for cold shipping as it is
not a premium. When receiving MT-2 it is recommended to store in the
Mixing: Add BW to the vial when you are ready to begin
MT-2 research. View the instructional youtube video on the PT-141 page to see
the reconstitution process.
Remove plastic flip top from vial to expose
rubber stopper. Needle will pierce the stopper making way inside the vial to
turn the white powder into a clear liquid.
Calculator: Add 100 units
(1ml) of water to the vial. 1ml/100 units will minimize the volume that you have
to inject and will simplify the arithmetic in your MT-2 experiment.
1ml syringe (U100), 1ml BW to reconstitute
Calculations for a
desired 0.5mg/500mcg dose:
Step 1= 1ml
Step 2= 10mg MT-II
Step 3= 1ml
Step 4= 500mcg dose
2-3 ticks on your insulin pin
(approximately 1/20th of a U100 syringe)
prefer to add more dilutent which works fine, take note of the volume increase.
Needles: 29-31 gauge X 1/2″, 1 CC (100 unit). That is a typical insulin
needle used to mix as well as inject. Use needles one time only. Once your
technique perfected, injections are almost painless.
Starting dose: Your
first injection should be a very small dose, for example .25mg (250mcg). See how
you react. Goal should be to feel nothing. Dose after dinner, before bed. Any
dosing chart stating that you should take a high dose (according to your weight)
is outdated and potentially dangerous.
Loading dose: Load with 0.5-1mg
once a day. People who have used doses in this range generally report getting
excellent results. Don’t worry if you miss occasional days. It will not make
much difference, focus on the cumulative effects.
Maintenance is taking doses less frequently than daily to avoid becoming darker
than you want. Yes, that will happen. With enough UVR, you will get much darker
than you have even been before. A maintenance dose can help prolong
super-physiological photo-protection MT-2 delivers.
Melanotan is a poor sunless tanner. UV (from sun or a tanning bed) light is
necessary to develop a tan. Without it, almost nothing happens. In other words,
NO UV = NO TAN. Well, user will pigment depending on skin type…. If you have
loaded for a full month and then start UV exposure, you (and your friends) will
be astounded by how fast you tan and how dark you get. Moreover, it is advisable
to keep areas of your skin that ordinarily get exposure covered up with a towel
and/or zinc oxide (nose/lips/face) and let less exposed areas develop
pigmentation first. Areas of skin that are typically sun-exposed in your day to
day life will respond more readily to the effects of the melanotan
Fat Loss: The melanocortin (MC) system is a signaling pathway
for leptin and insulin. The MC system is important for control of food intake
and body weight. MT-2 treatment results in adipocyte lipolysis. MT-2 increases
fatty acid oxidation(FAO) in which the MC5R plays a significant role. MT-2
improves insulin sensitivity through stimulating FAO in skeletal muscle tissue.
Reduced food intake from the anorectic response of MT-2 is primarily responsible
for weight loss.
Watch yourself: Your tan can sneak up on you. A tan
generally sets in 3 days after UV rays. Dose and expose yourself gradually to
UVR when tanning. Love your skin.
Avoid burning: You are protected from
burning mostly by your tan, not the MT-2 peptide. Therefore, don’t overdo the
rays at first. Start with only as much UV that you could tolerate without
burring before you began Melanotan. It should not take many weeks before you can
tolerate hours of strong sun without burning. Truly incredible for those who
have never experienced freedom to enjoy the sun.
Continue your regular
dosing protocol until you have reached your desired tan and do not want to
become darker. Cut injection frequency to once every 2, 3, 4, or even 7 days.
Experiment to find the frequency that gives the tan you want.
Store freeze dried and reconstituted peptides in the refrigerator.
have to inject MT-II?
Yes. The best, most efficient method of administering
Melanotan peptides are subcutaneous (subq) injections. Nasal sprays are
inconsistent and inefficient. No detectable levels were observed following oral
dosing – pills do not work.
There are many things you will need to consider before experimenting with this
peptide. Cyclic analogues (MT-II) have a wide range of peripheral effects and
systemic control is always going to pose an issue in clinical use. Needless to
say, MT-II is not an approved or regulated product. MT-II is legal to buy,
possess, etc. Variables such as skin type and individual goals need assessment.
Ask for critiques, plans and create a user log during use. Seasoned users are
generally more than happy to offer tricks of the trade.
When you start
supplementing a-MSH to tan keep in mind that tanning is literally a side effect.
The tanning response is, in reality, a physiological repair mechanism to instant
UV damage of the skin cells (epidermis/dermis). Melanocyte stimulating hormone
is not going to color your skin, it is going to make your own skin create its
own tan and that in turn creates protection. If you are looking to be some
bronzed beach God with perfectly uniform and specific color then you are better
off to going to mystic tan. Redheads, for example, naturally produce a variant
form of melanin that is yellowish-red (pheomelanin). Do not expect a brown tan
on a ginger body right away.
Know your skin type: Knowing your skin type
is just one detail which will help create a user log. There are 10s of thousands
of melanotan users worldwide who share the experience. Raise awareness and help
others who want to hear success stories, complications and failures.
I a good candidate for MT-II?
Melanotan is best suited for the folks with
skin types I & II. Prior sun damage, scars, tattoos, freckles, moles, hair
color, etc are deciding factors prospective MT-2 users consider. This is a
question handled best through asking the audience.
How should I dose
Start out small and build up. A typical starting dose is around .25mg
and max dose reaching 1mg.
Things to consider: There is no magic pill or
formula. Few dermatologists are familiar with Melanotan. The skin is a large,
unpredictable organ. Feel comfortable and confident with MT-II before use. Check
out as many before and after photos and user logs as you can. A skin type I
individual may have to commit months of dedication before dialing in their
desired results, be patient.
How much MT-II should I buy and how long
will it last?
Skin type I: 30-50mg
Skin type II: 20-30mg
Skin type III:
Should last entire summer or season
How soon will I begin to see
You should notice a change in your skin tone after three weeks. If
you have freckles, expect them to get darker before your actual skin color
How long will tan last?
A tan developed using Melanotan 2
lasts much longer than an ordinary tan. A well-tanned person returning from a
beach holiday will lose most of the tan in a month if they stop getting sun. But
if they had been using Melanotan 2 and continued on maintenance after returning,
they would still have most of their tan 3 months later.
Side effects of
Possible short-term side effects you should know about, including:
nausea, appetite loss, facial flushing and increased libido. These may be
noticeable during the first few days of treatment but should taper
Dosing an anti-histamine, such as Claritin (Loratadine), works to
eliminate sides such as nausea after injecting.
(PT-141) was developed from Melanotan 2 (MT-II), which was tested as a sunless
tanning agent. PT-141 is a metabolite of MT-II that lacks the C-terminal amide
function-stripping away tanning properties.
have shown bremelanotide to be effective in treating sexual dysfunction in both
men (erectile dysfunction or impotence) and women (sexual arousal disorder).
PT-141 is the only synthetic aphrodisiac. Unlike Viagra and other related
medications (PDE5s), PT-141 does not act upon the vascular system, but directly
increases sexual desire via the nervous system
Bremelanotide is a melanocortin peptide hormone. PT-141
binds to the melanocortin 4 receptor (MC4R) in particular. Nine out of ten
volunteers experienced sexual arousal in trials. The desire is one of the more
sought after effects unique to the peptide.
Although injected (subcutaneously), Bremelanotide has a unique
window of opportunity lasting six to 72 hours. In lab trials, female rats
exposed to PT-141 immediately began “flirting” with male rats for sex. Postures
and movements left no doubt in the male rats minds that they were in the
Women who took part in trials said that they felt a “tingling and a
throbbing” along with “a strong desire to have sex.” An initial flush occurs
post injection, followed by nausea which is dose dependent. For most, effects
generally do not take place until a couple hours post injection, peaking around
the four hour mark.
Men said PT-141 made them feel “younger and more
energetic” as well as sexually interested and aroused. “You’re ready to take
your pants off and go,” said user “a drug that makes you not only able to but
Dosing: Read as much as possible to gain clarity and align
expectations. Gradually dosing increases likelihood for success without sides. A
test dose of .25-.5mg on the first attempt is recommended. 1mg, give or take a
quarter, is the efficacious dose which yields the most hero stories reported by
Bremelanotide PT-141 Peptide:
in lyophilized form comes in 10mg and 2mg vial sizes (as pictured above -notice
the peptide volume -no filler present). Once reconstituted with bacteriostatic
water, PT-141 can be stored in the fridge for a couple months and remain potent.
Nasal sprays, pre-mixed PT-141, pills and loose powder are not legitimate forms
of Bremelanotide. There are successful reports of snorting and nasal spray
experiences…however they are few and far between.
Bacteriostatic water is used for reconstitution.
bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately
each 10 units on a U100 insulin syringe.
Example- 1ml(cc) bacteriostatic
water per 2mg PT-141 vial equates to a 1mg dose approximately every 50 units on
a U100 insulin syringe.
Recommended strategy for mixing and dosing would
be to reconstitute with the volume that yields a .1ml injection.
Example- 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a
1mg dose approximately each 10 units on a U100 insulin syringe.
.2ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose
approximately every 10 units on a U100 insulin syringe.
Human Growth Hormone (HGH)
Human Growth Hormone
Month 1: HGH 2 IU one injection every other day
2-4: HGH 3 IU one injection five days a week
Months 5-6: HGH 4 IU one
injection five days a week
4-6 month cycles are optimal, year round if you
are over age 35.
Human Growth Hormone (rHGH, HGH, or GH) is a protein
molecule consisting of 191 amino acids. Genetically engineered recombinant human
growth hormone is completely identical to the growth hormone made by the human
pituitary gland. Researchers have proven growth hormone therapy can reverse the
biological effects of aging. HGH is widely appreciated for aesthetics, not
necessarily as a performance enhancer.
HGH is released in pulses
that take place during the day. Growth hormone is rapidly converted in the liver
to its powerful growth promoting metabolite, Insulin like Growth Factor. IGF-1
is measured in the blood to determine the level of growth hormone secretion.
Most of the beneficial effects of human growth hormone are directly attributable
to IGF-1. Growth hormone replacement/stimulation is the most effective therapy
to reverse the effects of aging.
At age 30 people have people have
spent most of their lives with relatively high levels of HGH. HGH is responsible
for growth during childhood as well as for repair and regeneration of tissue. By
the time we are 30 our bodies no longer naturally produce enough GH to handle
the damage that is taking place. As this continues, we age. Increasing HGH in
our bodies, we can slow, or even reverse many of the manifestations of aging.
What HGH can do:
* Reduce excess body fat, especially abdominal
fat. (The reduction of abdominal fat is the single most profound effect of HGH
replacement in many people)
* Decrease in the waist to hip ratio. (Meaning
fat is removed primarily from around the waist where it is associated with a
high risk of coronary disease)
* Increase muscle mass. (and physical strength
if combined with moderate exercise)
* Reduce wrinkling of the skin and some
other effects of skin aging. (Compliments can be Melanotan and MT-II)
Re-grow certain internal organs that have atrophied with age.
* Increase bone
* Strengthen the immune system.
* Enhanced feeling of well
* Reverse cognitive decline.
* Stimulate production of the bone
marrow cells that produce red blood cells.
* Reduce the probability that you
will spend the last years of your life in a nursing home.
* HGH slows the
progression of cardiovascular disease, and reduces the risk of death from
cardiovascular disease, in individuals with natural growth hormone levels that
are below average for the age of the individual. HGH can also slow the
progression of cardiovascular disease by improving one’s cholesterol profile.
There is increasing evidence over the past year or two that maintaining healthy
growth hormone levels results in a stronger heart. Individuals with low growth
hormone levels have an overall increased risk of death due to cardiovascular
disease. Low growth hormone levels cause a particularly large increase in the
risk of stroke as compared with individuals receiving growth hormone
HGH takes several weeks to months of use benefit from
its effects. There are a number of substances that increase the natural
secretion of HGH. Some of them are amino acids. The relationship of certain
amino acids to growth hormone is complex and varies greatly among different
individuals and among individuals of different ages. All absolute and universal
statements made about this subject are clearly false.
HGH is a
peptide that comes in the form of lyophilized powder. Any other form that you
see advertised or run across is likely NOT the real deal. The only way to
administer true HGH is by sub-q or intramuscular injection. Be aware that HGH is
not anabolic by itself. Careful measures need to be in place during
Reconstituting common HGH, one vial contains powdered
freeze-dried HGH and the other vial contains sterile water with a bacteriostatic
preservative. When the user is ready to begin, a certain amount of the sterile
water is drawn out of the second vial (with a needle and syringe) and injected
into the first vial to dissolve the powdered HGH. The solution is then ready for
injection. The unused portion is to be kept refrigerated. Use reconstituted HGH
within 3 or 4 weeks.
HGH peptide is dissolved by the user because HGH
powder is much more durable. The dissolved HGH is very susceptible to being
attacked by bacteria and degraded by enzymes. HGH is normally refrigerated, but
if HGH powder is is left at room temperature for a few hours, no harm is done as
long as the room is not too warm. Sterile powdered HGH can even be left in a
cool room for days or weeks, but this is not a good idea. Even the powdered HGH
can deteriorate if the temperature rises slightly above normal room temperature
for any significant period of time.
The best way to begin HGH is to
start with a low dose and ease your way into higher doses. This will allow you
to avoid (or at least minimize) many of the more common sides of HGH such as
bloating and joint pain. Most can tolerate 1-2 IU per day with few sides. HGH
administration should be done on an empty stomach as fats and carbohydrates
blunt release. Natural production of GH is 1 IU, give or take a half. For
results in athletes the dosing should attempt to duplicate how the body releases
the hormone naturally. Learning how much and when to best dose is very
individual. My apologies for the dosing chart above.
growth hormone is best taken in conjunction with insulin, anabolics/androgens,
and thyroid hormone. Insulin is extremely effective with HGH as the injections
cause a down regulation of insulin sensitivity in the body.
life of HGH is 2 hours when injected sub-q with a four hour period which there
is a suppression of naturally produced GH. Intramuscular injections shorten the
half life. Subcutaneous injections over the long term can lead to spot
reduction. Whether or not HGH has any localized benefit from IM injection is
unknown, but speculated.
HGH is tightly regulated by the FDA, but HGH
is not a controlled substance on the federal level in the United
Insulin-like Growth Factor (Long-R3-IGF-1)
IGF-1 (Long R3 IGF-1)
Light: 20 mcg
Common: 40 mcg
Large: 80 mcg
injected post work out (PWO) or in the AM on non workout days for 4-6 week
Insulin-like Growth Factor (Long-R3-IGF-1), an 83 amino
acid analog of IGF-1 is a highly anabolic hormone released primarily in the
liver with the stimulus of growth hormone (HGH).
dried (lyophilized) IGF-1 (in powder state) should be stored in the freezer (-18
Each Long r3 IGF-1 kit contains:
of lyophilized Long R3 IGF-1
* 2 mls of 0.6% Acetic Acid (AA)
Sodium Chloride (NaCL) as buffer
Dilute the IGF-1 with 2mls of Acetic
Acid. Assuming (*DO NOT ASSUME*) AA will yield the correct pH balance of your
Note: This creates a concentration of 500mcg/ml. So each
1/10 of a ML is 50mcg’s.
Draw the desired amount of IGF in to a syringe.
Desired amount should be the approx dose you want to take.
Example- 2mls AA
used to reconstitute IGF-1 1mg vial means 5 units on a U100 insulin syringe
would equal 25mcg IGF-1
Pre-load your syringes at 5iu (25mcg IGF-1). Divide
your IGF-1 into 20 syringes to move to the freezer for storage.
prior to administration. Draw from your NaCL after thawed to fill the remainder
of your syringe with the buffer (up to 1ml typically).
test subject intramuscularly (IM) post workout. IGF-1 does not need to be
bilaterally or in the muscle trained.
Unknown whether injecting IGF-1 to
increase muscle growth is efficacious. Many believe in the value of IGF-1.
Growth Hormone Releasing Peptide (GHRP-6)
GHRP-6 (Growth Hormone Releasing Peptide)
Hormone Releasing Peptide (GHRP-6) is a peptide in the growth factor family
composed of six amino acids. It has strong effect on the release of Human Growth
Hormone (HGH). Dosed at night for anti-aging purposes and multiple times
throughout the day for anabolism. GHRP is often used in conjunction with GHRH
CJC-1295 to amplify GH pulse. GHRP-6 peptide is typically offered in 5mg
GHRP can be used effectively in the treatment of GH deficiency.
Main use is to promote food intake by stimulating hunger and aid in energy
metabolism. The major side effect being a significant increase in appetite due
to a stimulating the release of Ghrelin, a hormone released naturally in the
lining of the stomach and increases hunger and gastric emptying.
of increased HGH levels through GHRP-6 stimulation include: an increase in
strength, muscle mass and body fat loss, rejuvenation and strengthening of
joints, connective tissue and bone mass. Enhanced HGH secretion also leads to
the liver secreting more IGF-1, which is thought to be the primary anabolic
mechanism of action for Growth Hormone.
Mixing: Bacteriostatic water is
used for reconstitution. When diluted, peptide lasts a very long time when left
alone in the refrigerator (months).
Example- 2.5ml(cc) bacteriostatic
water per 5mg GHRP vial equates to a 100mcg dose approximately each 2-3 marks on
a U100 insulin syringe.
Example- 5ml(cc) bacteriostatic water per 5mg GHRP
vial equates to a 100mcg dose approximately every 5 marks on a U100 insulin
Dosing: The saturation dose of GHRP-6 has been determined to be
5mg GHRP = 5,000mcg
5,000mcg/100mcg = 50 100mcg GHRP
doses per 5mg
GHRP-6 may be the most cost effective secretalogue
Growth Hormone Releasing Hormone
Common: 100 mcg
Large: 250 mcg
Growth Hormone Releasing Hormone
(GHRH) CJC-1295 is a synthetic secretalogue, when injected stimulates HGH
release from the hypothalamus. Dosing GHRH once at night for anti-aging purposes
and multiple injections (1-3x) for anabolism. CJC-1295 has the ability to make
the body produce its own GH as compared to using synthetic HGH. GHRP-6 use in
conjunction with CJC-1295 is synergistic, amplifying the GH pulse
CJC-1295 is typically found in 2mg vials. Reconstitute with
BW. Inject subcutaneously.
Researchers report positive effects much like
that of HGH. Particularly energy, quality sleep, fat loss/metabolism, improved
skin quality, pumps in the gym.
Most common desirable form to find and
research with CJC-1295 (Growth Hormone Releasing Factor) is a modified GRF
(1-29), lacking the DAC (drug affinity complex). This GHRH has a short half
life. Post injection flush is common.”