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Growth Hormone Releasing Peptide Hormones

Growth Hormone Releasing Peptide Hormones

What types of Growth Hormone Releasing Hormones out there are worthy?

Growth Hormone Releasing Hormone Research Peptides:
– GRF (1-29) a.k.a. Sermorelin – Active-life is a few minutes
– Modified GRF (1-29) – Half-life is approximately 30 min
– CJC-1295 – Bio-active life continuing as long as days

Growth Hormone Releasing Hormone (GHRH) protein peptide pulses excreted from healthy pituitary glands cascading into polypeptide growth hormone. Peptide hormone benefits greatest when growth hormone releasing peptide is administered alongside the therapeutic peptide legitimate CJC-1295 (DAC) 2mg. Avoid paying for complicated manufacturing of legit CJC-1295 peptides as they are often mislabelled.

The administration of Growth Hormone Releasing Hormone in theory creates a pulse of growth hormone release which varies during the natural rise and fall of growth hormone peptide levels. Growth hormone releasing benefits from ghrh will be marginal if dosed during natural hgh trough – higher if administered during a natural rising growth hormone cascading pulse. Cheap modified growth releasing factor superior to Sermorelin Acetate extends bio active results; purchase peptides legal CJC1295 (Mod Grf 1-29) as best alternative to Sermorelin (Rx, $$).

Growth Hormone Releasing Peptides

What types of Growth Hormone Releasing Peptides are most desirable?

Growth Hormone Releasing Peptides (GHRPs):
– Ipamorelin is potent growth hormone releasing pentapeptide that does not increase cortisol or prolactin and dosage is user-friendly.
– GHRP-6 is very potent ghrelin agonist peptide having great effect stimulating growth hormone peptides release. Ghrp6 does not effect cortisol or prolactin at low doses (>100mcg).
– GHRP-2 is slightly more potent then GHRP-6 with less side effects experienced. Ghrp2 has stronger effect on growth hormones at all dosage peptide levels. 5mg GHRP2 vials often requiring more diluent to reconstitute product properly.
– Hexarelin Acetate is the strongest and more potent GHRP. Throughout all dosage levels the hexapeptide has the highest influence on cortisol and prolactin levels.

Important Note: GHRPs (Growth Hormone Releasing Peptides) are capable of creating a larger pulse of growth hormone on their own than Growth Hormone Releasing Hormone (GHRH) and they do this with much more consistency and predictability without regard to whether a natural wave or trough of growth hormone is currently taking place.

How Does Growth Hormone Releasing Hormone and Growth Hormone Releasing Peptides work together?

Well documented and established clinical research proves the concurrent administration of GHRH and GHRP results in synergistic release of growth hormone. Moreover, if Growth Hormone Releasing Hormone (GHRH) contributes a growth hormone amount quantified as #2 and Growth Hormone Releasing Peptide (GHRP) contributed a growth hormone amount quantified as the number 4 the total growth hormone release is not additive (i.e. 2 + 4 = 6). Rather the whole is greater than the sum of the parts such that 3 + 6 = 18.

Can Growth Hormone Releasing Hormone have beneficial effect without GHRP?

Problem with using only GHRH is that they are only effective when somatostatin is low. After listening to the body, user administration finds optimal time to dose within a trough (or when a growth hormone pulse is not occurring naturally) you will add little growth hormone releasing opportunity. If however ghrh 2mg administered during a wave of growth hormone pulse (somatostatin will not be active) you will add to growth hormone release potential.

Can Growth Hormone Releasing Peptides be used alone?

Yes, GHRPs are capable of creating a larger pulse of growth hormone on their own than GHRH and do this with much more consistency. Response from ghrelin hormones may vary during ghrp peptide hormone therapy.

GHRH + GHRP Peptide Stacks?

100-200mcg of your Growth Hormone Releasing Peptide of choice – dosing approximately 5-7 days a week by subcutaneous injections.

GHRPs can be used once, twice, three or four times a day for prolonged effect.
When dosing throughout the day separate the administrations by three hours.

191AA Growth Hormone

What are Human Growth Hormone (rHGH) and HGH Fragment 176-191?

The HGH Fragment is a modified form of amino acids 176-191 at the C-terminal region of the human growth hormone (HGH). Studies have shown that it works by mimicking the way natural HGH regulates fat metabolism without the adverse effects on insulin sensitivity or cell proliferation that is seen with rHGH. HGH fragment 176-191 stimulates lipolysis and inhibits lipogenesis.

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how to use bodybuilding peptide guide

Peptide Information

Insulin-like Growth Factor LR3 (IGF-1)

IGF-1 LR3 Dosage(Long R3 IGF-1):
Light: 25 mcg
Common: 50 mcg
Large: 100 mcg
IGF-1 is administered for one month, give or take a week.
Insulin-like Growth Factor (Long-R3 IGF-1), an 83 amino acid analog of IGF-1 is a highly anabolic hormone released primarily in the liver with the stimulus of growth hormone (HGH).

IGF-1 is the most potent growth factor found in the body and causes muscle cell hyperplasia.
Freeze dried (lyophilized) IGF-1 (in powder state) should be stored in the freezer (-18 degrees Celsius).
Example Long r3 IGF-1 kit contains:
1000mcg of lyophilized (freeze dried) Long R3 IGF-1
2 mls of 0.6% Acetic Acid (AA)
30ml Sodium Chloride (NaCL) as buffer
Dilute the IGF-1 peptide with 2mls of Acetic Acid (.6%). Assuming (*DO NOT ASSUME*) Acetic Acid (AA) will yield the correct pH balance of your research peptide.
Note: This creates a concentration of 500mcg/ml. So each 1/10 of a ML is 50mcg’s.

Draw the desired amount of IGF in to a syringe. Desired amount should be the approx. dosage wanted.
Example- 2mls AA used to reconstitute IGF-1 1mg vial means 5 units on a U100 insulin syringe would equal 25mcg IGF-1 LR3
Pre-load your syringes at 5iu (25mcg IGF-1). Divide your IGF-1 into 40 syringes for storage in the freezer.
Thaw prior to administration. Draw from your NaCL after thawed to buffer (.5ml is enough).

Unknown whether injecting IGF-1 to increase muscle growth is efficacious. Many believe in the value of this powerful growth factor.
It is possible to go into hypoglycemia fro IGF-1 supplementation. Effect is dose dependent.

(information in this thread gathered via the internet)
Melanotan peptides, PT-141, CJC-1295, GHRP-6, IGF-1 LR3, GH fragments, come in the form of freeze dried powder using Bacteriostatic Water (BW) for reconstruction and preservative. Research peptides are supplied in multiple-dose vials from which repeated withdrawals may be prepared for subcutaneous injection (administrated intramuscularly in rare instances).

Melanotan 1 – Melanotan is a synthetic (potent) version of melanocyte stimulating hormone (a-MSH). Afamelanotide treatment induces skin pigmentation through melanogenisis, the production of melanin. Melanin prevents cellular damage in the skin by absorbing, reflecting and refracting light. Melanotan reduces sun damage to UV exposed skin in those with sun allergies.

Melanotan 2 – Melanotan II is a cosmetic product that stimulates a natural increase in melanin production. Melanin is the main determinant of skin color in humans, a brown pigment which causes skin to become darker in appearance, instead of red, when exposed to UVR. Users of Melanotan II develop a gradual, natural tan with minimal sun exposure. Melanotropins useful for all skin types, particularly fair-skinned (Fitzpatrick skin type 1 & skin type 2).

Bremelanotide (PT-141) – Unexpected sexual arousal experienced by Melanotan 2 tanning trial subjects led to development of Bremelanotide PT-141. PT-141 does not act upon the vascular system, but the nervous system (cacading direct from the brain). Bremelanotide results are the world’s only synthetic aphrodisiac developed after Melanotan 2 (MT-II).
GH Releasing Peptide-6 – GHRP 6 is a synthetic hexapeptide (six amino acid peptide) that releases growth hormone release. High levels of growth hormone have been associated with fat loss, muscle gain, general well being and anti-aging effects. Ghrelin effect from GHRP-6 can cause hunger. Ipamorelin, Hexarelin and GHRP-2 also bestselling GHRP research peptides.
GHRH (CJC-1295) – CJC-1295 (GHRH) continuously elevates Human Growth Hormone (HGH) and IGF-1. In the healthy body, large amounts of growth hormone are stored within the pituitary. CJC-1295 DAC has been proven to stimulate slow wave sleep helping restore the body. Research Sermorelin, CJC-1293, CJC1295, Mod GRF 1-29 (best) research peptide.

Insulin-like Growth Factor LR3 – Insulin-like Growth Factor (Long-R3-IGF-1), analog of IGF-1 is a highly anabolic peptide released primarily in the liver with the stimulus of growth hormone. IGF-1 LR3 and IGF-1 DES popular glucose disposal agent analog peptides sold online. Dosage for IGF1 LR3 unspecific, whereas quick acting IGF DES pre-exercise administration recommended.

191AA Growth Hormone (HGH) – Human Growth Hormone (rHGH, HGH, or GH) is a protein molecule consisting of 191 amino acids. Genetically engineered recombinant growth hormone is completely identical to the growth hormone made by the human pituitary gland. Growth hormone helps body composition and is rapidly converted to its powerful growth promoting metabolite, Insulin like Growth Factor (IGF-1).

PEPTIDE INFO

Peptide Information

Peptides come in the form of lyophilized (freeze dried) powder. The amount of powder/product is stated in International Units (IU’s) or in Milligrams (MG).
Melanotan peptides (Melanotan 1 & Melanotan 2), PT-141 Bremelanotide, GH Fragment, Ipamorelin, CJC-1295 & GHRPs (GRHP-2 & GHRP-6), HGH, HCG, et cetera use Bacteriostatic Water (BW). Bacteriostatic Water for injection, USP is a sterile, nonpyrogenic preparation of water for injection containing 0.9% of benzyl alcohol added as a bacteriostatic preservative. It is supplied in a multiple-dose container from which repeated withdrawals may be made to dilute or dissolve drugs for injection. The pH is 5.7 (4.5 to 7.0)

For IGF use an acetic acid solution (.6%) which is 7 parts distilled water and 1 part vinegar to reconstitute. You must filter the distilled water and white wine vinegar through a sterile 20 micron syringe filter before use. Sodium Chloride (NaCl) is used to buffer the injection.

1.) Take an alcohol swab to the stopper of both your peptide vial and the vial of the diluent.

2.) Draw your preferred diluent (BW) with a 1cc syringe. Choose an amount that will make measuring the final product simple.

1ml(cc) per 10 mg vial of Melanotan would mean each 10 tick marks on a U100 slin syringe would equal 1mg of Melanotan
1ml(cc) per 10 IU vial of HGH would mean each 10 tick marks on a U100 slin syringe would equal 1 IU of HGH

3.) Take the syringe with the diluent and push it into the vial of lyophilized powder letting the diluent dissolve the peptide. Many (not all) peptides are sealed with vacuum pressure, be careful.

4.) After diluent has been added to the vial, gentling swirl the vial until the lyophilized powder has dissolved and you are left with a clear liquid. The peptide is now reconstructed, ready for measurement and usage.
5.) Store your now reconstituted research peptides in the refrigerator.
Peptide Measurement
After successfully reconstituting your peptide, measure the desired amount out for injection. Use a U100 insulin syringe to draw out and inject your product.

Since you know the amount of IU’s/MG’s in your vial, we divide this out as follows:
You will need to know the following to be successful: 1ml = 1cc = 100 IU’s

We take our dose from the label of the dry lyophilized powder and we divide that into the amount of diluent used.

Example- We used 1cc(ml) of water. We have a 10 IU vial of HGH.
From our formula above we know that 1cc = 100 IU’s, so we have 100 IU’s of water.
We now divide the 100 IU’s (the amount of our water) by 10 IU’s (the amount of our HGH)
100 IU / 10 IU = 10

This 10 will perfectly correspond with the markings on a U100 insulin syringe. In our example every 10 mark on our syringe will equal 1 IU of HGH. Want to draw out 2 IU’s of GH? ….draw out to the 20 mark on the syringe (1/5th of the syringe).
Say you have a 1mg vial and you add 1ML you get
1000mcg/1mL: 10 mcg per IU
1000mcg/2mL: 5 mcg per IU
Say you have a 10mg vial and you add 1ML you get
10mg/1mL: 1 mg per 10 IU
10mg/2mL: .5 mg per 10 IU
Say you have a 20mg vial and you add 1ML you get
20mg/1mL: 2 mg per 10 IU
20mg/2mL: 1 mg per 10 IU
Say you have a 10iu vial and you add 1ML you get
10iu/1mL: 1 iu per 10 IU (on the syringe – 1/10th the product)
10iu/2mL: 1 iu per 20 IU (on the syringe – still 1/10th the product)
Say you have a 5000iu vial and you add 1ML you get
5000iu/1mL: 500iu per 10 IU
5000iu/2mL: 250iu per 10 IU

Melanotan 1

Afamelanotide (M-I) Dose:
Light: .5mg
Common: 1mg
Large: 2mg
Melanotan 1 synthetic melanocyte stimulating hormone (a-MSH) induces skin pigmentation through melanogenisis, melanin production. Melanin prevents cellular damage in the skin by absorbing, reflecting and refracting light. Melanotan reduces sun damage to UV exposed skin transforming cells to produce dark protective melanin.

Melanotan Results: Melanotan favors production of eumelanin (black/brown) over pheomelanin pigment. Injecting this linear amino acid Melanotan 1 peptide offers super-physiological levels of tanning ability.

Melanotan 2

Melanotan 2 Dose:
Begin: 100mcg
Light: 250mcg
Common: 500mcg
Stout: 1mg
Large: 1.5mg
Max: 2mg
What is Melanotan 2
Melanotan II analog of alpha-melanocyte stimulating hormone (a-MSH). Melanotan peptides are safe and efficacious with growing long term data. Melanotan 2 is a freeze dried peptide sealed in a sterile multi-use vial. Generic 10mg Melanotan II:

Melanotan injections act on melanocytes to stimulate melanin production. Melanin is the body’s pigment responsible for a photoprotective safe tan.

Bremelanotide

Bremelanotide PT 141 Dose:
Light: .5mg
Common: 1mg
Large: 2mg
Bremelanotide PT-141 was developed from Melanotan 2 (MT-II). PT-141 is a metabolite of melanocyte stimulating hormone that targets desire.

Treatment: PT-141 is the only synthetic aphrodisiac. The aphrodisiac effects of Bremelanotide are in a class of its own. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Nine out of ten volunteers experienced sexual arousal in clinical trials. Unlike Viagra and other related medications (PDE5s – blood pushers), PT-141 acts upon the nervous system. Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 have known synergy.

Men’s Journal Magazine: …it took hold. I felt a great surge of affection (greater than any regular level of arousal). My body tingled and I developed an erection that wouldn’t quit. For two hours the drug wouldn’t let me out of its grasp — nor my wife out of mine. -Frederick Kaufman

Females: Women who took part in trials said that they felt a “tingling and a throbbing” along with “a strong desire to have sex.” An initial flush occurs post injection, followed by nausea which is dose dependent. For most, effects generally do not take place until a couple hours post injection, peaking around the four hour mark. Men said PT-141 made them feel “younger and more energetic” as well as sexually interested and aroused. “You’re ready to take your pants off and go,” said user “a product that makes you not only able to but eager to.”
Bremelanotide PT-141 Peptide: Bremelanotide comes in 10mg vials. As a lifestyle peptide, the 10mg product is a lot to consume and may offer up to 20 doses when dosing conservatively. Research PT-141 reconstituted with bacteriostatic water remains potent in the fridge for months.
Window of Opportunity: Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours. In lab trials female rats exposed to PT-141 began “flirting” with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood. The human PT-141 date is one where the dosage precedes the activity by at least a couple hours. When the stars align, hours after the injection, …this is your window of opportunity, enjoy.
Mixing: Bacteriostatic water is used for reconstitution.
Example- 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example- 1ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 50 units on a U100 insulin syringe.
Recommended strategy for mixing and dosing would be to reconstitute with the volume that yields a .1ml injection.
Example- 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example- .2ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 10 units on a U100 insulin syringe.
Dosing: Read as much as possible to gain clarity and align expectations. Gradually dosing increases likelihood for success without sides. A test dose of .25-.5mg on the first attempt is recommended. 1mg, give or take a quarter, is the efficacious dose which yields the most positive reports by users.

Ghrp-6

GHRP-6 Hexapeptide Dosage:
Light: 50mcg
Common: 100mcg
Large: 150mcg
Growth Hormone Releasing Peptide (GHRP-6) is a peptide in the growth factor family. It has strong effect on the release of Human Growth Hormone (HGH) in a specific and dose-related manner. GHRP can be effectively used in the treatment of growth hormone (GH) deficiency. Growth hormone releasing hexapeptide works by signaling the pituitary gland to begin growth hormone secretion.

Increased GH and IGF-1 levels are desirable for those looking to improve physique. Human growth hormone has been known to enhance immune response and stimulate the immune system, particularly older subjects. Dosed at night for anti-aging purposes and multiple times throughout the day for anabolism. GHRP is often used in conjunction with GHRH CJC-1295 (mod GRF 1-29) to amplify growth hormone pulse. Avoid fats and carbohydrate a half hour on each side of dosing GHRP-6.

Bodybuilders and athletes dose GHRP in an effort to build more muscle and burn fat. Some GHRP-6 users include it in their post cycle therapy (PCT). Cycling GHRP-6 in the off weeks from IGF/GH cycles is also becoming prevalent. Researchers wish to kick-start their body into producing their own natural GH & IGF, while gaining as if they remained on the GH/IGF peptides.

GHRP-6′s main use is to promote food intake by stimulating hunger and aid in energy metabolism. The major side effect being a significant increase in appetite due to a stimulating the release of Ghrelin (about 20 minutes post injection), a hormone released naturally in the lining of the stomach and increases hunger and gastric emptying. This is why GHRP-6 can be used in the treatment of cachexia (wasting), eating disorders and obesity.

Benefits of increased HGH levels through GHRP-6 stimulation include: an increase in strength, muscle mass and body fat loss, rejuvenation and strengthening of joints, connective tissue and bone mass. Enhanced HGH secretion also leads to the liver secreting more IGF-1, which is thought to be the primary anabolic mechanism of action for Growth Hormone.
Bodybuilding Peptide GHRP-6:

Mixing: Bacteriostatic water is used for reconstitution. When diluted, peptide lasts a very long time when left alone in the refrigerator (months)

Example- 2.5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately each 2-3 marks on a U100 insulin syringe.
Example- 5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately every 5 marks on a U100 insulin syringe.

Dosing: The saturation dose of GHRP-6 has been determined to be around 100mcg. More is not better in regards to this secretagogue

5mg GHRP = 5,000mcg

5,000mcg/100mcg = 50 100mcg GHRP doses per 5mg

Growth Hormone Releasing Hormone (CJC-1295)

Modified GRF 1-29 (GHRH) CJC1295 Dosage:
Light: 25mcg
Common: 50mcg
Large: 100mcg
Growth Hormone Releasing Hormone (GHRH) CJC-1295 is a synthetic secretagogue which stimulates HGH release. In the human body, large amounts of growth hormone are stored in the pituitary. GHRH affects the number of secreting cells and the amount they are able to secrete. GHRH Analog research peptides sold online are a fantastic addition to GHRP (GHRP-6 & GHRP-2).

Dosing GHRH once at night for anti-aging purposes and multiple injections (1-3x) for anabolism. CJC-1295 has the ability to make the body produce its own GH as compared to using synthetic HGH. GHRP-6 use in conjunction with CJC-1295 is synergistic, amplifying the GH pulse considerably. Synthetic GH side effects can be experienced with pure growth factor peptides. Researchers also report positive effects much like that of HGH. Particularly energy, quality sleep, fat loss/metabolism, improved skin quality, pumps in the gym and numb/tingles at extremities.

CJC-1295 is typically found in 2mg vials. Reconstitute with BW. Inject subcutaneously. Generally best to invest in shorter acting modified GRF 1-29 as CJC-1295 manufacturing is difficult and fragile. GHRH (mod GRF 1-29) dose has 30 minute half life, superior to that of Sermorelin. Post injection flush is common. Ipamorelin is increasingly popular research peptide alternative. Genuine CJC-1295 DAC bloats male researchers, best to avoid real CJC-1295.

191AA Growth Hormone, Basic peptide guide, Bremelanotide, CJC-1295, GH Releasing Peptide-6, GHRH, Guide, guides, hgh, IGF, IGF-1 LR3, Melanotan 1, Melanotan 2, PT-141

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